The todays paper of the day is about stuttering. When I googled stuttering I found a funny quote: “Stuttering is Ok. Because what I say is worth repeating”. This quote highlights already the most prominent feature of stuttering: the involuntary repetitions of sounds and words which disturb the fluency of speech. Moreover, involuntary prolongations of sounds and involuntary silent pauses in which the person is unable to say anything, are also characteristics of stuttering. Sometimes people stutter in uncomfortable stressful situations, sometimes the stuttering is a persistant disease (also called chronic perseverative stuttering - CPS). The latter is the focus of the paper of Jolanta Góral-Półrola et al. (2015). The neurodevelopmental hypothesis of fluency of speech “suggests that the main symptoms in stuttering disorders are the result of integrated genetic, developmental, neurological, and social factors.” Based on this hypothesis, Góral-Półrola et al. (2015) looked at the gene expression of a 26 years old CPS patient. The focus was on stress related genes. Interestingly, “the expression of almost all tested genes, with the exception of IL1, in patient’s leukocytes were lower than in the control group.” This either means a lower stress load of this patient or insufficient stress response and protection of the cells. Of course, a single patient is not enough for significant study results, but having in mind that the most of us were already in a stressfull situation in which they started stutering, it seems quite logical that chronic stuttering may be connected to an decreased stress tolerance due to low stress gene expression. Just as remark: "Changes in gene expression associated with cell stress in the patient with chronic persevarative stuttering"
Góral-Półrola et al. (2015).
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IdeaI love to increase my general science knowledge by reading papers from different fields of science. Here I share some of them. Archiv
März 2018
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